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Tapentadol is a centrally acting analgesic medication used for the management of moderate to severe pain. It is classified as an opioid analgesic and works by binding to opioid receptors in the brain and spinal cord, thereby altering the perception of pain.

Tapentadol is unique compared to traditional opioids in that it also inhibits the reuptake of norepinephrine, a neurotransmitter involved in pain modulation. This dual mechanism of action provides pain relief while potentially reducing some of the side effects associated with traditional opioids, such as respiratory depression and constipation.